Dr. Miguel Aguileta earned his B.Sc. in biomedical research from the National Autonomous University of Mexico, his M.Sc. in neuroscience from McGill University in Montreal, Canada and his Ph.D. in biotechnology from Ghent University, Belgium. During his graduate studies, Dr. Aguileta conducted research in different fields, including amyotrophic lateral sclerosis (ALS), Parkinson’s disease (Parkin and PINK1) and cell death mechanisms (intrinsic and extrinsic pathways). Dr. Aguileta pursued a brief (two-year) postdoctoral fellowship in Cologne, Germany, where he uncovered an immune response triggered by Huntingtin aggregates. In addition to his passion for investigating neurodegenerative diseases, he has a particular interest in posttranslational modifications. In 2019, he joined the laboratory of Dr. Patrik Brundin at Van Andel Institute as a postdoctoral fellow.
Dr. Ehraz Anis graduated from Aligarh Muslim University, India, with a bachelor’s degree in biochemistry. He then completed a master’s degree in biotechnology at Hamdard University, India. Dr. Anis worked on the 6-OHDA murine model of Parkinson’s disease (PD) and studied mitochondrial dysfunction and oxidative stress in PD for his Ph.D. dissertation at Aligarh Muslim University. He is currently studying the role vermiform appendix plays in PD pathology at Van Andel Institute.
Dr. Sonia George received her Ph.D. in neuroscience from the University of Melbourne, where she studied animal models of Parkinson’s disease, further characterizing and using the transgenic A53T alpha-synuclein mouse to model Parkinson’s disease. Sonia started her work focusing on previously undescribed behavioral abnormalities in these animals. In 2009, she began working with other transgenic models of Parkinson’s disease to further understand disease mechanisms while a postdoctoral researcher at Johns Hopkins University and University of Minnesota. Sonia then moved to Lund University to focus her research on Alzheimer’s disease, the leading cause of late-onset dementia. Using a transgenic mouse model of Alzheimer’s disease, she tested potential therapeutics and also studied the stereotypical spread of pathology over time in a mouse model of Alzheimer’s disease. Using a neurotoxin to chemically kill the brain cells in the brain structure where pathology first appears this model, Sonia prevented the further spread of pathology. In the Brundin Laboratory at Van Andel Research Institute, she continues using her skills to model Parkinson’s disease in mice to elucidate disease mechanisms, test potential therapeutics and investigate the role of inflammation in the spread of brain pathology in this disease.
Emily graduated from Michigan Technological University with a bachelor’s degree in biology and mathematical sciences. She has been a part of Dr. Patrik Brundin’s lab since 2015, focusing on Parkinson’s disease research. Her current work includes optimizing lab workflow and experimental protocols, training new lab members, and supporting the members of the lab in their neurodegeneration research using skills and techniques such as immunohistochemistry, small rodent work and cell culture.
Alli graduated from Hope college in Holland, Michigan with a composite degree in neuroscience. She joined Dr. Brundin’s lab in 2019 and assists laboratory scientists in their Parkinson’s-focused research. Her current work includes optimizing laboratory workflow and training new lab members in experimental protocols.
Dr. Gabriela Mercado graduated from the University of Chile, with a Ph.D. in biological sciences. In the past years, her research focus has been on investigated the role of protein homeostasis dysfunction in Parkinson´s disease. Currently, she studies the mechanism underlying the pathological propagation of protein misfolding leading to neuronal dysfunction in the olfactory system of PD animal models.
Dr. Emmanuel Quansah is an expert in molecular biology. He earned his B.Sc. in molecular biology and biotechnology from University of Cape Coast in Ghana followed by an M.Sc. in pharmaceutical biotechnology and a Ph.D. in molecular neurobiology from De Montfort University in the United Kingdom. His graduate work focused on the effects of the medication Ritalin (methylphenidate) on the developing brain. As a postdoctoral fellow in the laboratory of Dr. Patrik Brundin at Van Andel Institute, his work has centered on misfolded protein propagation in Parkinson’s disease. Over his academic career, Dr. Quansah has received several awards for his work, including the High-Flyers Scholarship from De Montfort University.
Dr. Jennifer Steiner graduated from Vanderbilt University (Nashville, Tenn., USA) with a Ph.D. in neuroscience. After a postdoctoral fellowship with Dr. Patrik Brundin at Lund University (Sweden), where she focused on modeling parkinsonism in multiple models, she moved with Dr. Brundin to VAI and shifted to laboratory management. She has worked for Dr. Brundin for more than 10 years, and helps push everyone in the lab’s research on Parkinson’s disease forward.
Dr. Lucas Stetzik graduated from the College of Wooster with a bachelor’s degree in biochemistry and molecular biology. He completed his Ph.D. in integrated biosciences with a focus on behavioral neuroendocrinology at the University of Akron. He went on to complete a postdoctoral fellowship at the University of Florida studying olfaction using in vivo calcium imaging. Currently, he is working to develop an engrailed1 synucleinopathy mouse model.
Carla graduated from Grand Valley State University with a bachelor’s degree in biology. She joined Dr. Brundin’s lab in early 2021 after working for Charles River Laboratories as a pathology lab technician, bringing with her multidisciplinary laboratory experience and enthusiasm for biomedical research. Her role in the lab is assisting laboratory scientists with their research on Parkinson’s disease and neurodegeneration.
Dr. Aoji Xie graduated from Huazhong University of Science and Technology, Wuhan, China with a bachelor’s degree in pharmacy. She completed her Ph.D. degree in neuroscience at Huazhong University of Science and Technology studying tau-induced neurodegeneration in Alzheimer’s disease. Her current project is investigating the links between the microbiome, epigenome, and Parkinson’s disease.